Biomedical Advances in HIV Prevention: Social and Behavioral by Douglas Krakower, Kenneth H. Mayer (auth.), Lisa A. Eaton,

By Douglas Krakower, Kenneth H. Mayer (auth.), Lisa A. Eaton, Seth C. Kalichman (eds.)

Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives

Lisa A. Eaton and Seth C. Kalichman, editors

Three a long time into the epidemic, greatly is understood approximately HIV and its transmission, extra everyone is residing with the sickness, and the virus is not any longer obvious as a dying sentence. yet new humans stay contaminated with HIV every year, making prevention suggestions which are medically powerful and behaviorally attractive as pressing a concern as ever.

Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives assembles the most recent advancements, obstacles to implementation, and probabilities for--and challengesto--future development. strategies equivalent to pre-exposure prophylaxis (antiretroviral regimens for the high-risk uninfected) and therapy as prevention (early use of paintings to minimize infectiousness of latest sufferers) are tested, as are present findings on ongoing prevention and remedy concerns.

Contributors remove darkness from the advanced realities entailing adherence, declaring technological, behavioral, and cultural roadblocks in addition to possibilities to noticeably decrease an infection charges. precise up to the moment insurance includes:

  • Prevention providers for individuals residing with HIV
  • Adherence to HIV therapy as prevention and pre-exposure prophylaxis
  • Advocating for rectal microbicides and secure lubricants
  • Mental healthiness and substance use within the scale-up of HIV prevention
  • Risk repayment in line with HIV prevention
  • Implementing biomedical HIV prevention advances: experiences from South Africa, Uganda, Australia, Thailand, usa, Ecuador, and Peru

Researchers, practitioners, and coverage makers operating within the fields of HIV/AIDS and public healthiness will glance towards BiomedicalAdvancesinHIVPrevention: Social and Behavioral Perspectives as either a way for constructing and assessing present courses and a blueprint for the subsequent new release of prevention efforts.

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Additional info for Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives

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On the other hand, adherence may not turn out to be an issue as the product’s effectiveness may serve as strong motivation for adherence. Regardless, adherence is likely to be a challenge that will require a concerted effort to overcome and PrEP programs will need to include practical and proven adherence support programs. 2 Translating Pre-Exposure Prophylaxis Evidence into Practice and Public Health Impact 33 Fig. 2 Correlation between PrEP effectiveness trials and adherence as measured using detectable drug levels Varying Adherence Leading to Varying Efficacy Both the CAPRISA 004 and iPrEX trials showed that effectiveness was closely linked to levels of adherence and presence of drug.

Dumond JB, Patterson KB, Pecha AL, Werner RE, Andrews E, Damle B, et al. Maraviroc concentrates in the cervicovaginal fluid and vaginal tissue of HIV-negative women. J Acquir Immune Defic Syndr. 2009;51(5):546–53. 78. Mutua G, Sanders E, Mugo P, Anzala O, Haberer JE, Bangsberg D, et al. Safety and adherence to intermittent pre-exposure prophylaxis (PrEP) for HIV-1 in African men who have sex with men and female sex workers. PLoS One. 2012;7(4):e33103. 79. Van der Elst EM,M, Mugo P, et al. High acceptability of HIV pre-exposure prophylaxis but challenges in adherence and use: qualitative insights from a Phase I trial of intermittent and daily PrEP in at-risk populations in Kenya.

Antiviral Res. 2011;90(3):168–82. 23. Abdool Karim SS, Richardson BA, Ramjee G, Hoffman IF, Chirenje ZM, Taha T, et al. 5 % PRO2000 gel for the prevention of HIV infection in women. AIDS. 2011;25(7):957–66. 24. McCormack S, Ramjee G, Kamali A, Rees H, Crook AM, Gafos M, et al. PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial. Lancet. 2010;376(9749):1329–37. 25. Van Damme L, Govinden R, Mirembe FM, Guedou F, Solomon S, Becker ML, et al.

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Biomedical Advances in HIV Prevention: Social and Behavioral by Douglas Krakower, Kenneth H. Mayer (auth.), Lisa A. Eaton,
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